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Aspreviously mentioned, Tregs can behave as inflammatory cells like mast cells that also releaseGrB to increase permeability of the ECM to lymphokines and cells by degradation offibronectin, collagen, and laminin (Buzza 2005).

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Acquisition of serial images permits the generation of time-intensity curves forcontrast passage through the brain. The cell in the center ofthe micrograph has been cut in a planecloser to the cell surface and reveals these same densities as a branching structure (doublearrows)

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